Provides financial assistance to address the continued unmet health needs in the Delta Region through cooperation among health care professionals, institutions of higher education, research institutions, and economic development entities.

Funds rural communities to drive measurable improvements in access to integrated, coordinated treatment and recovery services for substance use disorder (SUD), including opioid use disorder (OUD). Its long-term aim is to reduce morbidity and mortality associated with SUD and enable sustained recovery and well-being.

Offers federal grant funding for projects that help Appalachian communities that have been affected by job losses in coal mining, coal power plant operations, and coal-related supply chain industries. ARC prioritizes POWER funding for projects that will produce economic opportunities.

Supports community engagement projects with funding for artist fees to engage Southern guest film directors; traditional, visual, and performing artists; or writers from inside or outside of the presenter's state. Artist fee support will be awarded for the following: film, traditional arts, visual arts, performing arts, and literary arts.